Most reactions are from the Adenovirus vaccine, but you can have a reaction from any shot given to any animal

Legs stuck straight out for 6 hours - Tendons locked

Puppies start signs 3 hours to 10 days after administering.

• Fever.
• Sluggishness.
• Loss of appetite.
• Facial or paw swelling and/or hives.
• Vomiting.
• Diarrhea.
• Pain or swelling around the injection site.
• Collapse, difficulty breathing, and seizures (anaphylactic shock)

Additional signs we have encountered related to the Adenovirus Type 2 vaccine.

• Swelling specifically in the muzzle, around the eyes, and pads of the feet
• Drooling
• Consistent drinking
• Belly bloating
• Rear legs stuck in the stretched position
• Blood in the stools
• Uncontrollable shaking
• Pupils not dilating
• Eyes changing to a grey color and can turn the eye white. (friends puppy)
• Temperatures after anaphylactic shock from 104 – 107 degrees
• Death

What we did to help make the puppies through the reaction.

• Submerged the puppies in cold water until fever went down to 102
• Sub Q fluids
• Keep allowing and helping the puppy drink electrolyte water
• Checking the temperature hourly
• Do not keep moving your puppy. The muscles tense so much their body will be very sore
• Rear legs stuck in the stretched position